Thierry Sempere joins the Strategic Committee of Op2Lysis


Thierry Sempere, who was recently appointed as new President of WICAP Op2Lysis, the holding that represents all WiSEEDers who invested in Op2Lysis within the crowdfunding campaign for the first round of fundraising, will join the Strategic Committee of Op2Lysis for its next meeting, in replacement of Alexis Nogues. The professional background of Thierry in the pharmaceutical industry, which includes a sound international operational experience, will bring a strong contribution to the Strategic Committee, in complementarity with other members.

We welcome Thierry in this new assignment, and we thank Alexis for his contribution to our project.

The 6 members of the Strategic Committe of Op2Lysis are now the following persons : Patrick Cassagne, Christophe Gaudin, Philippe Monteyne, Jean-Claude Muller, Jérôme Parcq et Thierry Sempere.

Op2Lysis to work on a market research with Efficient Innovation

Efficient Innovation was selected to perform a qualitative market research, which will help us to enhance our understanding of market expectation about our product and to reinforce the most critical characteristics of our target product profile.

This work will be funded in part by the competitive cluster Medicen Paris Region in a three-way contract, with a joint participation of Conseil Régional d’Ile de France and European Union Feder funds.

Welcome to Marie-Julie Guichard, in charge of translational and regulatory studies

Marie-Julie Guichard joined us on last 29 October 2018. She will be in charge of translational and regulatory studies.

Marie-Julie is a PhD from the University of Louvain in Belgium where she worked on the preclinical development of a drug treatment for cystic fibrosis patients. During her training period, she also benefited from a US research experience in a biotech company in Cambridge, MA.

Op2Lysis has been selected to join Neighborhood, a life science innovation center developed by Voisin Consulting Life Sciences that supports health tech startups in providing strategic and development regulatory coaching to favor growth. Marie-Julie will be working at Neighborhood office space and will benefit from a regulatory mentoring adapted to her new responsibilities

Last October 29th was also the World Stroke Day, which is a very good sign. We wish Marie-Julie every success in her new assignment, which is a key role for Op2Lysis preclinical development progress.

Who are we? Episode #7 Estelle Louet

Through this mini-series of articles, we want to present you the talents of each member of the team.

  • Estelle, can you introduce yourself briefly?

E.L : I am Project Engineer at Op2Lysis. I am also a PhD student, within a collaborative industrial agreement between Op2Lysis and Inserm research unit U1237.

I obtained a Bachelor at the University of Fribourg and a Master in medical biology, with a specialization in neuroscience, at the University of Zurich. I obtained all my degrees in Switzerland, which is the country where I was born

  • Why did you decide to join the Op2Lysis team?

E.L : I was very pleased to join the Op2lysis team. First, because I think that the project is very interesting, both from the scientific and the human perspectives. I am proud to be a part of this project. I always wanted to work for a company that is at the edge of technology and that uses this science to serve the public health care. Additionally, I benefit from the opportunity of strengthening my professional experience and skills beyond my academic training, through this private-public combination.

  • What is the strength of the technology developed by Op2Lysis?

E.L : Our technology is based on perfect knowledge of stroke mechanisms as well as tPA mechanisms of action, which will allow best use of our drug candidate in patients with an intracerebral hemorrhage.

Our product is specifically designed to treat patients with intracerebral hemorrhage easily and with best safety.

  • What is your personal contribution to Op2lysis ?

E.L : As a Project Engineer at Op2Lysis, my responsibility is to conduct the scientific experiments which are required to allow further development of our technology. Therefore, I use daily my scientific skills and technical knowledge, as well as the analytic capacity that I acquired all along my training.

I can participate in some decisions about company communication. I would like to be able to bring new perspectives for the company through my PhD project.

Op2Lysis SAS announced the closing of a first round of fundraising

Discover this announcement in a press release


Op2Lysis is an Innovative Young Company

Op2Lysis has obtained the Innovative Young Company label from the French Ministry of Higher Education and Research. Together with CIFRE contract, this label is the second key support received by Op2Lysis over these last few weeks to strengthen its innovation.

Op2Lysis ranked TOP 10 at Big Booster 2018 and was selected for camps in Boston and Shanghai.

Op2Lysis has been ranked as the 7th best start up (out of the initially 100 companies selected at the beginning of the competition) at the Big Booster Demo Days 2018, in Lyon (France) and is now a member of the 2018 Big Booster Class. This success offers the opportunity to fly to Boston and to Shanghai in the next few months in order to consolidate existing partnerships and to open new opportunities for business with the USA and China.


More information on Big Booster:

The CIFRE Convention, for acceleration of R&D activity

On April 18th, 2018, Op2Lysis has been granted by the Agence Nationale de la Recherche et de la Technologie (ANRT) for its application to CIFRE (Conventions Industrielles de Formation par la REcherche) on the research work to be performed by Estelle LOUET. This positive feedback will reinfoce the R&D capacity of Op2Lysis, while favoring proper training of the research staff. The Convention will favor public-private exchanges between Inserm-Unicaen UMRS1237 research lab, which is based in Caen, and Op2Lysis.

About the CIFRE Convention

For over 30 years, CIFRE (Conventions Industrielles de Formation par la REcherche) provides funding grants to French companies when they hire young PhD students to work on collaborative projects in partnership with public labs. Thesis defense based on this work is to occur within 3 years. CIFRE subventions are entirely funded by the French Ministère de l’Enseignement supérieur, de la Recherche et de l’Innovation. The Agence Nationale de la Recherche et de la Technologie (ANRT) is in charge of implementation.

More information :


Brain Week, March 12-18, 2018

Want to know even more about your brain ?

You should attend the 20th edition of the “brain week” standing from the 12th to the 18th of March. This event is organized every year by the French Society of Neurosciences with the purpose of raising awareness of the largest audience on the role and impact of research in various fields of neurosciences and to better understand our role in this puzzle. To check if there is an event close to your place, please consult (in French):


Stroke symptoms

How to identify stroke symptoms in friends or relatives, including yourself ?

Stroke symptoms are sudden and require immediate management. Therefore, it is critical to know these signs, so that treatment can be quickly initiated
If the following occurs:

  • Sudden trouble in speaking or understanding other people (aphasia) ;
  • Sudden numbness or paralysis of one side of the face ;
  • Sudden numbness or paralysis of one arm or one leg (hemiplégia) ;
  • Sudden loss of sight (often in one signle eye) or double vision ;
  • Sudden loss of balance or body movement coordination ;

Then, call emergency number, to ensure fast management and transfer to a Stroke Unit..

Even if symptoms go away, you should quickly see a doctor.