What is the mRS and why is it important for Op2Lysis?

What is the mRS and why is it important for Op2Lysis?

The modified Rankin Score (mRS) is used by health professionals to measure the degree of disability following a stroke in a patient. This disability scale includes 6 levels of score ranging from level 0 for patients with no symptoms to level 5 for patients with major disabilities and total loss of autonomy. A separate category, Level 6, is usually added by the medical profession for patients who do not survive their stroke.

The mRS scale, deemed reliable and easy to use, is recognised by the health authorities for the registration of a medicinal product on the market but also recognized by health insurances, since this scale also allows them to determine the cost of managing a patient based on level of disability.

It is therefore used as the primary clinical criterion in most clinical trials for the registration of new stroke treatments. Standardized interviews to obtain a mRS score are recommended every 3 months (90 days) after discharge from the hospital.

The clinical development program of O2L-001 will therefore also call on the mRS score. Our ambition is to reduce the number of patients with severe disabilities and severe socio-economic dependence.

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Tiffany Le Carff administrator